Dosages (Yerba Mansa) : 4–8 grams root/day; 1–2 drops fluid tincture 2–3 ×/day (Hobbs); 20 to 60 drops fresh root tincture (fresh 1:2, dry 1:5, 60% alcohol) to 5 ×/day; 2–4 oz cold root infusion to 5 ×/day (Moore1).
Contraindications, Interactions, and Side Effects (Yerba Mansa) : Avoid during pregnancy (Hobbs). In animal studies, the sedative effect of roots and the compound methyleugenol potentiates the hypnotic action of thiopental, pentobarbital, and hexobarbital. Also enhances the central depressant effect of chlorpromazine. Urinary irritant (HAD).
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