GREATER PERIWINKLE VINCA MAJOR

GREATER PERIWINKLE (Vinca major L.) +

Most authors suggest that the greater and lesser periwinkle are generically interchangeable medicinally,
and I agree, so far.

Activities (Greater Periwinkle) :
- Anticholinesterase (1; HH2); Antihemorrhagic (1; WOI); Antilactagogue (f; WOI); Astringent (1; GMH); Hypotensive (1; HH2); Laxative (f; GMH); Negative Inotropic (1; HH2); Parasympatholytic (1; HH2); Positive Inotropic (1; HH2); Tonic (f; GMH).

Indications (Greater Periwinkle) :
- Bleeding (1; GMH; WOI); Cardiopathy (1; HH2); Congestion (f; GMH); Constipation (f; GMH); Convulsion (f; GMH); Cramp (f; GMH); Diarrhea (f; GMH); Enterosis (f; GMH); Enuresis (f; HH2); Epistaxis (f; GMH); Hemorrhoid (f; HH2; GMH); High Blood Pressure (1; HH2); Hysteria (f; GMH); Leukorrhea (f; HH2); Menorrhagia (1; HH2; GMH); Nightmare (f; GMH); Pulmonosis (f; GMH); Sore Throat (f; GMH); Tonsilosis (f; GMH).

Dosages (Greater Periwinkle) :
- 2–4 g dry herb/cup tea to 3 ×/day (HH2).

Extracts (Greater Periwinkle):
- Aqueous extract (1.82 g leaf/50 ml water reduces in vitro (in human serum) cholinesterase activity by 50% (HH2). Mix of vincamine and vincine lower blood pressure IC27–40 = 5–10 mg/kg ivn rat LD50 (mixed alkaloids) = 37 mg/kg ivn mouse (HH2).