Herbal Medicine
WILD INDIGO (Baptisia tinctoria (L.) R. Br) +
Synonym : Sophora tinctoria L.
Activities (Wild Indigo) : Antidipsomanic (1; FNF); Antiinflammatory (f; FAD); Antileukemic (1; FNF); Antimelanomic (1; FNF); Antipyretic (f; PH2; PNC); Antiseptic (f; MAD; PNC); Antitumor (1; FNF); Apoptotic (1; FNF); Choleretic (f; FAD); Depurative (f; PH2); Emetic (f; DEM; FAD); Emmenagogue (f; PH2); Estrogenic (1; FAD; FNF; PH2; PNC); Expectorant (f; PH2); Hepatotonic (f; MAD); Immunostimulant (1; FAD; PH2; PNC); Laxative (f; EFS; FAD; HHB); Leukoctyogenic (1; PHR); Phagocytotic (1; HAD; PH2; PNC); Tonic (f; DEM).
Indications (Wild Indigo) : Adenopathy (f; PH2); Alcoholism (1; FNF); Amenorrhea (f; MAD); Angina (f; MAD; PHR); Bleeding (f; DEM); Boil (f; PNC); Bruise (f; DEM; FAD); Cancer (1; FNF; JLH); Cancer, breast (1; FNF; JLH); Cancer, colon (1; FNF; JLH); Cancer, ovary (1; FNF; JLH); Cancer, stomach (1; FNF; JLH); Catarrh (f; PH2); Cholera (f; MAD); Cold (f; PHR); Colic (1; MAD); Confusion (f; PH2); Constipation (f; EFS; FAD; HHB); Cramp (f; DEM); Diarrhea (f; MAD); Diphtheria (f; MAD; PHR); Dysentery (f; MAD); Enterosis (f; MAD); Felon (f; JLH); Fever (f; HHB; PHR; PH2; PNC); Flu (f; MAD; PH2); Gastrosis (f; MAD); Gingivosis (f; PNC); Gonorrhea (f; DEM; PH2); Head Cold (f; PH2; PHR); Hemoptysis (f; DEM); Hepatosis (f; HHB); Immunodepression (1; FAD; PH2; PNC); Infection (f; PH2; PNC); Inflammation (f; DEM; FAD; JLH; PH2); Influenza (f; PHR); Leukorrhea (f; PHR); Leukemia (1; FNF); Lymphadenosis (f; PHR); Lymphoma (1; FNF); Malaria (f; MAD; PHR); Mastosis (f; PH2); Melanoma (1; FNF); Mucososis (f; PH2); Nephrosis (f; DEM); Neuroblastoma (1; FNF); Pharyngosis (f; PH2; PNC); Proctosis (f; MAD); Prolapse (f; MAD); Respirosis (f; PH2); Rheumatism (f; DEM); Scarlet Fever (f; MAD; PHR); Sore (f; DEM; FAD; PH2); Sore Throat (f; FAD; PH2); Sprain (f; DEM); Stomatosis (f; PHR); Swelling (f; JLH); Tonsilosis (f; PH2; PNC); Toothache (f; DEM; FAD); Tumor (1; FNF); Typhoid (f; PHR); Typhus (f; MAD; PHR); Vaginosis (f; PNC); VD (f; DEM); Vomiting (f; DEM); Whitlow (f; JLH); Wound (f; DEM; PHR).
Dosages (Wild Indigo) : 2–5 ml root tincture (PNC); 0.5–1 g root 3 ×/day (PHR).
Contraindications, Interactions, and Side Effects (Wild Indigo) : Class 2b, 2d (AHP). Not for long-term use except under supervision of a qualified practitioner (AHP). Contraindicated in pregnancy (PH2). “Hazards and/or side effects not known for proper therapeutic dosages” (PH2). Large doses (e.g., 30 g) are potentially harmful and may induce cramps; mild intoxication with diarrhea, GI symptoms, nausea, and vomiting (FAD; PHR; PH2).
Extracts (Wild Indigo) : Isoflavones are estrogenic (PNC). Ethanol extracts stimulate phagocytosis, raising leukocyte counts (PHR). Polysaccharides stimulate antibody production (PNC). Baptisia tinctoria, like red clover, may contain biochanin-A, daidzein, and genistein. Genistein induces apoptosis and inhibits mitosis in rat ovarian granulosa in vitro, and has inhibited all sorts of tumors in vitro, breast, carcinoma, gastric, gastrointestinal, leukemia, lymphocytic leukemia, medullablastoma, melanoma, neuroblastoma, and ovarian cancer types. Reportedly, daidzein inhibited differentiation in human leukemia HL-60 cells, B16 melanoma cells, and HL-60 cells.
Hit: 363
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