VERVAIN VERBENA OFFICINALIS

VERVAIN (Verbena officinalis L.) ++

Activities (Vervain) :
Adaptogen (f; FAD); Analgesic (1; APA; CRC; PH2; WAM); Antibacterial (1; HH2); Antidepressant (f; APA; PNC); Antiedemic (1; APA; PH2); Antiinflammatory (1; APA; FAD; HHB; PHR); Antileukemic (1; HH2); Antipyretic (f; CRC; WOI); Antiseptic (1; FAD; FNF; HH2; PHR); Antispasmodic (f; CRC; MAD; PNC); Antitumor (1; PH2); Antitussive (1; APA; PHR; PH2); Antiviral (1; FNF; PHR); Aphrodisiac (f; CRC; HDR); Astringent (1; CRC; HDR; PH2); Bitter (1; WAM); CNS Depressant (1; FNF); Cytotoxic (1; PH2); Decongestant (1; APA); Depurative (f; MAD); Diaphoretic (1; CRC; FEL; MAD; PNC; WAM); Digestive (f; APA; PNC); Diuretic (1; APA; FAD; HHB; HH2; MAD; WAM); Emetic (f; CRC; FEL; PNC); Emmenagogue (f; APA; CRC; HHB); Expectorant (1; APA; CRC; FEL; HHB; MAD); Hypotensive (1; APA); Lactagogue (1; APA; CRC; FAD; HHB; MAB; PH2); Laxative (f; CRC); Litholytic (f; CRC); Nervine (1; CRC; MAD; PNC; WAM); Parasympathomimetic (1; APA; PNC); Rubefacient (f; CRC); Secretolytic (1; APA; PHR; PH2); Sedative (1; WAM); Sialagogue (1; PHR); Thymoleptic (1; CAN); Tonic (f; CRC; FEL; MAD; PNC); Uterocontractant (1; APA); Uterotonic (1; CAN; CRC; FNF); Vermifuge (f; CRC; WOI); Vulnerary (f; CRC; WOI).

Indications (Vervain) :
Acne (f; APA); Adenopathy (f; JLH); Alactea (1; PHR); Amenorrhea (f; HH2; MAD); Anemia (f; CRC; MAD); Angina (f; HH2); Anorexia (f; FEL); Arthrosis (f; HH2; PHR; PH2); Asthma (f; HH2; MAD; PHR; PH2); Bacteria (1; HH2); Bladder Stone (f; MAD); Bleeding (f; MAD); Bronchosis (f; CRC); Bruise (f; FEL; PHR; PH2); Burn (f; PH2); Calculus (f; CRC); Cancer (1; CRC; JLH; PH2); Cancer, colon (1; FNF; JLH); Cancer, neck (1; FNF; JLH); Cancer, parotid (1; FNF; JLH); Cancer, scrotum (1; CRC; JLH); Cancer, spleen (1; CRC; JLH); Cancer, testicle (1; CRC; JLH); Cancer, throat (1; CRC; JLH); Cancer, viscera (1; CRC; JLH); Carbuncle (f; PH2); Cerebrosis (f; PH2); Chlorosis (f; MAD; PHR); Cholecystosis (f; HH2; PH2); Cold (f; FEL; HH2; PH2; PNC); Congestion (1; APA); Constipation (f; CRC); Convulsion (f; PH2); Cough (1; HH2; MAD; PHR; PH2; PNC); Cramp (f; APA; CRC; MAD; PHR; PH2; PNC); Cystosis (f; MAD); Debility (f; APA; FEL); Depression (f; APA; HH2; MAD; PNC); Dermatosis (f; PHR; PH2); Dislocation (f; PHR); Dropsy (f; CRC; MAD; PHR); Dysmenorrhea (f; APA; CRC; FEL; MAD; PHR; PH2; WOI); Dyspepsia (f; PHR; PH2); Dysuria (f; CRC); Eczema (f; CRC; HH2; MAD); Edema (1; APA; CRC; MAD; PH2); Enterosis (f; FEL); Exanthema (f; MAD); Fatigue (f; PHR; PH2); Fever (1; APA; CRC; FEL; MAD; PNC; WAM; WOI); Flu (1; FNF; PHR); Gas (f; CRC); Gastrosis (f; FEL; PH2); Glossosis (f; MAD); Gout (f; HH2; MAD; PHR; PH2); Gravel (f; FEL; MAD); Headache (f; APA; CEB; CRC; MAD); Hematuria (f; MAD); Hemorrhoid (f; CRC); Hemostasis (f; MAD); Hepatosis (f; DEM; FAD; HH2; MAD; PH2); High Blood Pressure (1; APA); Hyperactivity (1; WAM); Hypophosis (f; MAD); Induration (f; JLH); Inflammation (1; APA; FAD; HHB; PHR); Infection (1; WAM); Infertility (f; MAD); Insomnia (1; CRC; HHB; WAM); Itch (f; PHR; PH2); Jaundice (f; APA; MAD; PNC); Kidney Stone (1; X7860196); Leukemia (1; HH2); Lichen (f; MAD); Lochia (f; MAD); Malaria (f; CRC; FAD; MAD; PH2); Melancholia (CAN); Menopause (f; PHR); Migraine (f; APA; HH2); Mucososis (f; PH2); Nephrosis (f; DEM; MAD; PHR; PH2); Nervousness (1; WAM); Neuropathy (f; CRC; HH2; MAD); Neurasthenia (f; APA; MAD); Neurosis (f; APA; PHR; PH2); Ophthalmia (f; CRC); Otosis (1; WAM); Pain (1; APA; CRC; MAD; PH2; WAM); Parotosis (f; JLH); Pertussis (f; PHR; PH2); Pharyngosis (f; PH2); Pleurisy (f; CRC); Polyp (f; JLH); Psoriasis (f; MAD); Respirosis (f; MAD; PH2); Rheumatism (f; HH2; MAD; PHR; PH2); Salmonella (1; HH2); Shigella (1; HH2); Sore (1; APA; MAD); Sore Throat (f; HH2; MAD; PH2); Splenosis (f; FAD; JLH; MAD); Stomatosis (f; PH2); Stone (f; CEB; CRC); Swelling (1; APA; PH2; WOI); Toothache (f; MAD); Trigeminosis (f; MAD); Tumor (1; PH2); Ulcer (f; CRC; MAD); Uterosis (f; CRC; MAD); UTI (f; PHR; PH2); Virus (1; FNF; PHR); Water Retention (1; APA; FAD; HHB; HH2; MAD; WAM); Worm (f; CRC; FEL; WOI); Wound (f; APA; MAD).

Dosages (Vervain) :
1.5–4 g to 3 ×/day (HH2); 4.5–9 g, as often happens, is the Chinese dose (PH2); 1 tsp herb/cup water 1–4 ×/day (APA); 2–4 g dry herb, or in tea, 3 ×/day (CAN); infusion of 5–20 g herb/liter water, take 2–4 g up to 3 ×/day (PH2); 1–2 tsp liquid herb extract (MAD); 2–4 ml liquid herb extract (APA; PH2; PNC); 2–4 ml liquid herb extract (1:1 in 25% ethanol) 3 ×/day (CAN); 5–10 ml herb tincture (1:1 in 40% ethanol) 3 ×/day (CAN).

Contraindications, Interactions, and Side Effects (Vervain) :
Class 2b (AHP), without stating the reason, perhaps rosmarinic acid refers to gonadotropic and lactagogue activity. CAN notes no toxicity or side effects for vervain itself, but adds that high doses of verbenalin can cause CNS paralysis, convulsions, and stupor. Excessive doses may interfere with blood pressure and hormone therapy. Reportedly abortifacient and oxytocic, it should not be taken in pregnancy. Excessive use should be avoided (CAN).

Extracts (Vervain) :
Animal or in vitro models demonstrate antiinflammatory, antitussive, lactagogue, secretolytic, and sialagogue activities (PHR). Fruits extracts used for dysmenorrhea and oligolactea. The lactagogue properties of vervain are often attributed to aucubin. A luteinizing action is attributed to inhibition of gonadotropic action on the posterior lobe of the pituitary. Verbenalin is uterotonic. LD50 extract 9000 mg/kg orl mus (HH2), LD50 ethanol extract 250 mg/kg ipr mus (HH2).