RED ROOT SAGE

RED ROOT SAGE (Salvia miltiorrhiza Bunge) +++

Activities (Red Root Sage) :
Alterative (f; FAY); Antiaging (f; AKT); Antiaggregant (1; APA; LAF); Antiandrogenic (1; LAF); Antiallergic (1; ABS; FNF); Antianginal (1; APA); Antiarthritic (f; FAY); Antibacterial (1; HH2; LAF); Anticarcinomic (1; KEB); Antihypoxic (1; KEB); Antiinflammatory (1; AKT; LAF); Antimutagenic (1; LAF); Antioxidant (1; LAF); Antipyretic (1; HH2); Antiseptic (1; HH2); Antispasmodic (f; FAY; LMP); Antithrombic (2; KEB); Astringent (1; FAY); Bitter (f; AKT; LMP); Calcium Antagonist (1; KEB); Cardioprotective (1; ABS; FNF); Cardiotonic (1; LAF); Circulotonic (f; AKT; FAY); Fibrinolytic (2; KEB); Fungicide (1; FAY); Hepatoregenerative (1; APA); Hepatoprotective (1; HH2); Hypocholesterolemic (1; LAF); Hypotensive (2; APA; KEB); Lipolytic (f; KEB); Negative Inotropic (1; HH2); Nephroprotective (1; KEB); Sedative (1; APA; FAY; LMP); Swelling (f; HH2); Tonic (f; FAY); Tranquilizer (f; FAY); Vasodilator (2; FAY; HH2; KEB); Vulnerary (f; FAY; LMP).

Indications (Red Root Sage) :
Acne (2; KEB; LAF); Alcoholism (1; AKT); Allergy (1; ABS; FNF); Alopecia (f; AKT; LAF); Altitude Sickness (1; DAA; KEB); Amenorrhea (f; DAA; LAF; HH2); Anemia (f; FAY); Angina (2; APA; FAY; HH2; LAF); Arthrosis (f; FAY); Bacteria (1; FAY; FAY; HH2; LAF); Backache (f; FAY); Bleeding (f; DAA); Buerger’s Disease (2; KEB); Cancer (1; DAA; JLH; LAF); Carbuncle (f; HH2); Carcinoma (1; KEB); Cardiopathy (2; ABS; AKT; APA; FAY; FNF; HH2); Childbirth (f; LMP); Cough (f; HH2); Cramp (1; APA; FAY; LMP); Cystosis (f; DAA; LMP); Dementia (1; AKT); Dermatosis (1; LAF); Diabetes (f; HH2); Dysmenorrhea (f; APA; DAA; LAF); Eczema (1; LAF); Embolism (f; DAA); Enterosis (1; APA; DAA; LAF; LMP); Fever (1; HH2); Fibrosis (2; AKT; KEB); Fracture (1; KEB); Fungus (1; FAY); Furuncle (f; DAA; HH2); Gas (1; APA); Gastrosis (f; LMP); Glaucoma (1; AKT); Gray Hair (f; AKT; LAF); High Cholesterol (1; LAF); Heart Attack (2; KEB); Hepatosis (2; APA; DAA; FAY; HH2; KEB; MAB); High Blood Pressure (2; AKT; APA; DAA; KEB); High Cholesterol (1; LAF); Hives (f; DAA); Hyperviscosity (2; KEB); Infection (1; DAA; FAY; HH2); Inflammation (1; AKT; LAF; LMP); Insomnia (1; APA; FAY; HH2; LAF; LMP); Ischemia (2; AKT; KEB); Leukemia (f; DAA; JLH); Leukorrhea (f; LAF); Lupus (1; APA); Lymphoma (1; KEB); Mastosis (f; DAA); Metrorrhagia (f; DAA; LAF); Mycosis (1; FAY); Myocardiopathy (1; FAY; HH2); Nephrosis (f; DAA; LMP); Nervousness (1; APA; FAY; HH2; LMP); Neurasthenia (f; DAA); Neuropathy (1; KEB); Osteosis (f; LMP); Pain (f; DAA; LMP); Palpitation (f; DAA; KEB); Parturition (f; FAY); Psoriasis (1; LAF); Restenosis (f; AKT); Scleroderma (2; KEB); Splenosis (f; HH2); Staphylococcus (1; DAA; FAY; HH2); Stenosis (1; APA); Stroke (2; APA; KEB); Thrombosis (2; DAA; HH2; KEB); Tonsilosis (f; FAY); Tuberculosis (1; DAA; HH2); Ulcer (f; LMP); Uterrhagia (f; APA).

Dosages (Red Root Sage) :
3–5 g crude herb (AKT); 3–15 g root in tea (HH2); 6–15 g dry root/day (APA); 5–15(-30) g root/day (FAY); extract of 60 g crude root/day 2–4 weeks to 9 months (FAY); 2–6 g dry root/day or 4–12 ml fluid extract (1:2) (KEB).

Contraindications, Interactions, and Side Effects (Red Root Sage) :
Class 1 (AHP). Not covered (KOM). Tinctures may cause pruritus, reduced appetite, or stomachache (AHP). Dan Shen increases prothrombin time after warfarin; dangerous to take with coumadin (J. Emerg. Med. 18(1):22). Scarcely toxic (LAF).

Extracts (Red Root Sage) :
Aqueous extract LD50 = 80,500 mg/kg ipr mus (HH2). (Kyeong- Man; 1999). Inhibition of mast cell degranulation by tanshinones from the roots of Salvia miltiorrhiza. (Planta Medica 65: 654–5; 1999). The author found that four diterpene tanshinones were involved in inhibiting beta-hexosaminidase (an enzyme released with histamine when mast cells are immunologically activated). He also confirmed the inhibition of mast cell degranulation of an allergen IgE response-evoked cell sample. Cells were treated with the tanshinones for only 10 minutes. 15,16-dihydrotanshinone had the greatest antiallergic activity, more so even than quercetin, but less so than clinically used pharmaceuticals such as azelastine and ketotifen. (Kyeong-Man, 1999).