Dosages (Prickly Poppy) : 30 mimims oil (DEP); thimble full of seeds as emetic (DEP).
Contraindications, Interactions, and Side Effects (Prickly Poppy) : Ingestion of the seed oil can cause anemia, diarrhea, dysentery, high-tension glaucoma, and vomiting due to the ‘carcinogenic’ alkaloid, sanguinarine. Toxicity is due to interaction of sanguinarine and 11-oxo-triacontanoic acid. Milk of cows fed prickly poppy can cause glaucoma (WO2). LD50 of argemone oil = 9 ml/kg ipr mouse; sanguinarine 18 mg/kg (WBB). Seeds contain berberine, which may be helpful in MDR-resistant tuberculosis (JAD).
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