MAYAPPLE AMERICAN MANDRAKE

MAYAPPLE, AMERICAN MANDRAKE (Podophyllum peltatum L.) X

Activities (Mayapple)
Acaricide (1; CRC); Allergenic (1; FAD); Alterative (1; CRC); Anticancer (1; CRC; FNF); Antiherpetic (1; FNF); Antimitotic (1; PHR; PH2); Antiseptic (1; FNF); Antitumor (1; CRC; FNF); Antiviral (1; FNF); Aperitif (f; FEL); Bitter (1; CRC); Cholagogue (1; CRC; FEL; HHB); Choleretic (f; APA); Emetic (1; CRC; FAD); Hepatotonic (f; CRC); Hydragogue (1; CRC); Laxative (1; APA; CRC; DEM; FAD; FEL); Myelosuppressant (1; CRC); Narcotic (f; CEB); Poison (1; CRC); Sialagogue (f; FEL); Tonic (1; CRC); Vermifuge (1; CRC; DEM; HHB).

Indications (Mayapple)
Allergy (1; CRC); Amenorrhea (f; CRC; FEL); Anorexia (f; FEL); Arthrosis (f; APA); Atony (f; FEL); Atrophy (f; DEM); Biliousness (f; CRC); Bladder Stone (f; MAD); Boil (f; DEM); Bronchosis (f; MAD); Cancer (1; APA; CRC; FAD; FNF); Cancer, brain (1; CRC); Cancer, testicle (1; CRC); Cholera (f; MAD); Colitis (f; MAD); Condylomata (2; CRC; KOM; PH2); Congestion (f; MAD); Constipation (1; APA; CRC; DEM; FAD; FEL); Cough (f; CEB); Cystosis (f; FEL; MAD); Deafness (f; CEB; DEM); Dermatosis (1; CRC; MAD); Diarrhea (f; MAD); Dropsy (f; CRC; FEL; MAD); Dysentery (f; CRC; MAD); Dysmenorrhea (f; FEL); Dyspepsia (f; FEL); Enterosis (f; FEL; MAD); Enuresis (f; MAD); Fever (1; FAD; FEL); Gastrosis (f; FEL; MAD); Hepatosis (f; APA; CRC; FAD; FEL; MAD); Herpes (1; FNF); Hodgkin’s Disease (1; CRC); Incontinence (f; FEL); Infection (1; FNF); Inflammation (1; CEB; CRC); Jaundice (f; APA; CRC; FAD); Keratosis (1; CRC); Leukemia (1; APA; FNF); Lymphoma (1; APA; FNF); Malaria (1; FEL; FNF); Migraine (f; MAD); Myosis (f; DEM); Neuralgia (f; MAD); Pleurisy (f; CEB); Prostatosis (f; CRC); Psoriasis (1; APA); Pulmonosis (f; MAD); Rheumatism (f; APA; CRC; FEL; MAD); Scrofula (f; CRC; FEL; MAD); Sore (f; DEM); Stomatosis (1; FNF); Syphilis (f; APA; FAD; FEL); Ticks (1; CRC); Tumor (1; CRC; FNF); Ulcer (f; DEM); VD (1; CRC); Virus (1; FNF); Wart (2; APA; CRC; PHR; PH2); Worm (1; APA; CRC; DEM; HHB).

Dosages (Mayapple)
Do not take it (JAD); exclusively for external application, 1.5–3 g root (KOM; PH2); 0.5–2.5 g rhizome (MAD); 1.5–3 g rhizome fluid extract (KOM); 2.5–7.5 g rhizome tincture (KOM); 1–1.5 g rhizome tincture (MAD).

Contraindications, Interactions, and Side Effects (Mayapple) : Class 2b, 3 (AHP). Commission E reports contraindications for rhizome and resin external use in pregnancy. To be used 1–2 times weekly on skin surfaces not exceeding 15 cm2 (AEH). The resin is potentially lethal if ingested, and three deaths have been attributed to oral ingestion or topical application. An intrauterine death has been reported in a woman treated for vulvar warts (LRNP, January 1992). Etoposide is a semisynthetic derivative.