MAGNOLIA VINE SCHISANDRA CHINENSIS

MAGNOLIA VINE (Schisandra chinensis (Turcz.) Baill.) +

Synonym:
Kadsura chinensis Turcz.

Activities (Magnolia Vine) :
Adaptogen (1; AKT; APA; FAY; LAF; SKY); Anorectic (1; APA); Antacid (1; FAY); Antiaging (f; AKT); Antibacterial (1; FAY; LAF); Anticonvulsant (1; APA; LAF; PH2); Antidepressant (1; AKT; APA; KEB; LAF); Antifatigue (1; LAF); Antiinflammatory (1; AKT; KEB; PH2); Antineurotic (f; DAA); Antimutagenic (1; LAF); Antinecrotic (1; KEB); Antioxidant (1; APA; KEB; LAF; PH2); Antiradicular (1; X10616967); Antiseptic (1; APA); Antisialagogue (f; LAF); Antitumor (1; KEB; PH2); Antitussive (1; APA; DAA; FAY; LAF; PED); Aphrodisiac (f; DAA); Astringent (1; AKT; APA); Bitter (PED); Cardiotonic (1; AKT; LAF); Cerebrotonic (f; FAY); Choleretic (f; FAY); CNS Depressant (1; APA; DAA; FAY; KEB; LMP; PED); CNS Stimulant (1; DAA; FAY; KEB; LAF; LMP); Digestive (f; PED); Expectorant (1; FAY; KEB; LAF; PED); Gonadotropic (1; KEB); Hepatoprotective (2; APA; KEB; LAF; PED; PH2; SKY); Immunodepressant (1; LAF); Immunostimulant (1; FAY; LAF); Memorigenic (1; AKT; KEB); Myorelaxant (1; APA); Nephrotonic (f; FAY); Neuroleptic (1; PH2); Nervine (f; KEB); Pectoral (f; LMP); Respirastimulant (1; APA; KEB; LAF); Sedative (f; AKT; KEB; PH2); Sialagogue Potentiator (1; X8787787); Spermagenic (f; SHB); Tonic (f; AKT; APA); Tranquilizer (1; APA; LAF); Uterotonic (1; APA; FAY; LAF); Vasodilator (1; LAF); Vermifuge (1; PH2).

Indications (Magnolia Vine) :
Allergy (f; DAA; LMP); Amnesia (f; DAA; SHB; X11207061); Anxiety (f; PH2); Asthma (f; APA; LAF; LMP); Ataxia (1; KEB); Bacteria (1; FAY; LAF); Cancer (1; HH2; KEB; LAF; PH2; SKY); Cancer, skin (1; HH2); Chemotherapy Support (1; SKY); Circulosis (f; LMP); Cold (1; SKY); Convulsion (1; APA; LAF; PH2); Cough (1; AKT; APA; FAY; LAF; PED; PH2); Debility (f; LMP); Dementia (f; LMP); Depression (1; AKT; APA; KEB; LAF; SHB); Dermatosis (f; DAA; LMP); Diabetes (f; DAA); Diarrhea (f; APA; FAY; LAF; PH2); Dysentery (f; DAA; LMP); Dyspnea (f; PH2); Dystrophy (1; KEB). Enterosis (f; FAY; PH2); Enuresis (f; PH2); Fatigue (1; APA; SKY); Gonorrhea (f; DAA); Hepatosis (2; AKT; APA; DAA; KEB; LAF; PH2; SKY); Immunodepression (1; FAY; LAF); Impotence (f; APA; LAF); Infection (1; FAY); Inflammation (1; AKT; KEB; PH2); Insomnia (f; AKT; APA; DAA; KEB; LAF; PH2); Ischemia (f; AKT); Itch (f; DAA; LMP); Meniere’s Syndrome (1; KEB); Necrosis (1; KEB); Nephrosis (f; APA; FAY); Nervousness (1; AKT; APA; KEB; LAF; PH2); Neurasthenia (f; AKT; APA; FAY; LAF; PH2); Neuropathy (f; DAA); Night Sweats (f; DAA; FAY); Palpitation (f; AKT); Paralysis (2; KEB); Parkinson’s Disease (2; KEB); Parturition (1; KEB); Pollakiuria (f; PH2); Polyuria (f; DAA; LAF); Psychosis (2; KEB); Pulmonosis (f; AKT); Senile Dementia (1; KEB); Senility (f; LMP); Shock (f; FAY); Spermatorrhea (f; DAA; PH2); Stress (1; APA; SKY); Stroke (2; KEB); Thirst (1; APA); Tuberculosis (f; DAA); Tumor (1; KEB; PH2); Virus (f; DAA); Worm (1; PH2). Not covered by Commission E (KOM).

Dosages (Magnolia Vine) :
3–9 g powdered herb (AKT); 250–500 mg fruit 1–2 ×/day (APA); 1.5–6 g fruit (LAF); 1.5–15 g fruit (FAY); 5 g crushed fruit/100 ml water, divided into 3 doses/day (APA); 1 tsp fresh fruit (PED); 0.5 g dry fruit (PED); 0.5 g dry fruit:3 ml alcohol/2 ml water (PED); 1.5–6 g dry fruit/day or 3–12 ml fluid extract (1:2) (KEB); 2–4 ml fruit tincture 3 ×/day (SKY).

Contraindications, Interactions, and Side Effects (Magnolia Vine) :
Class 1. Rarely, appetite suppression, dyspepsia, and itch are attendant (AHP; LAF). Leaves and fruits are considered food in the Orient (FAC). Contraindicated in pregnancy except to facilitate childbirth (KEB).

Extracts (Magnolia Vine) :
“Lignans regenerate liver tissue damaged by harmful influences such as viral hepatosis and alcohol. Lignans lower blood levels of serum glutamic pyruvic transaminase (SGPT), a marker for infective hepatosis and other liver disorders” (SKY). Lignans improve activities requiring concentration and fine coordination in humans (KEB). Several contained lignans are antilipoperoxidants, and stimulate superoxide dismutase and catalase (BRU). Gomisin A protects against hepatocarcinogenesis and liver damage in various animal models via induction of hepatic enzyme systems and proliferation of the endoplasmic reticulum of liver cells. It is being studied as a human hepatoprotectant. Schisanhenol protects rat heart mitochondria from adriamycin toxicity without antagonizing its antitumor activity (KEB). Schisanhenol and, less so, schisandrin B, protect rat brain from oxidative stress (KEB). Foster and Yue (1992) note that the drug has been clinically tried in more than 5000 hepatitis cases, successfully lowering SGPT levels 84–97.9% (FAY). Schisandra is hepatoprotective against acetaminophen, aflatoxin, CCl4, chloroform, galactosamine, gossypol acetic acid, and thioacetamide. Schisandra in 189 patients with hepatitis C returned alanine-transferase to normal, and increased liver protein and glycogen synthesis. Alcohol extracts help regenerate liver tissues (SHB).