LONG PEPPER PIPER LONGUM

LONG PEPPER (Piper longum L.) +++

Activities (Long Pepper) :
Abortifacient (f; KAB; MPI; SKJ); Alterative (f; KAP; MPI); Analgesic (1; WOI); Anesthetic (1; WOI); Antiallergic (1; MPI); Antianaphylactic (f; MPI); Antibacterial (1; MPI; WOI); Anticonvulsant (f; PR13:561); Antifertility (1; MPI); Antigiardial (1; PR13:561); Antiinflammatory (f; WOI); Antiseptic (1; KAP); Antitubercular (1; WOI); Aphrodisiac (f; DEP; KAB; KAP); Cardiotonic (f; KAP); Carminative (f; DEP; KAB; SUW; WOI); Cholagogue (f; MPI; WOI); Collyrium (f; KAB); Counterirritant (f; WOI); Diaphoretic (f; SUW); Emmenagogue (f; DEP; KAB; MPI); Energetic (f; SUW); Errhine (f; KAB); Expectorant (f; DEP); Fungicide (f; KAP); Hematinic (f; WOI); Hepatoprotective (1; PR13:561); Immunostimulant (1; PR13:561); Insecticide (1; MPI); Insectifuge (1; MPI); Larvicide (f; WOI); Laxative (f; DEP; HHB; KAB); Protisticide (1; PR13:561); Rubefacient (f; KAP); Sedative (f; MPI; WOI); Sialagogue (1; WOI); Stimulant (f; SUW); Stomachic (f; HHB; SKJ); Tonic (f; MPI; WOI); Vermifuge (1; HHB; KAB; MPI).

Indications (Long Pepper) :
Allergy (1; MPI); Anaphylaxis (1; MPI); Anorexia (f; MPI); Apoplexy (f; DEP); Arthrosis (f; KAB); Ascites (f; SKJ); Asthma (f; MPI; WOI); Bacteria (1; MPI; WOI); Bite (f; DEP); Bleeding (f; DEP; KAP; MPI); Bronchosis (f; KAB; MPI; WOI); Callus (f; JLH); Cancer (f; JLH; KAB); Cancer, abdomen (f; JLH); Cancer, breast (f; JLH); Cancer, colon (f; JLH); Cancer, feet (f; JLH); Cancer, liver (f; JLH); Cancer, mouth (f; JLH); Cancer, nose (f; JLH); Cancer, spleen (f; JLH); Cancer, stomach (f; JLH); Cancer, throat (f; JLH); Cancer, uvula (f; JLH); Cancer, womb (f; JLH); Catarrh (f; DEP); Childbirth (f; KAB; KAP; MPI); Cholecystosis (f; MPI); Cholera (f; MPI); Cold (f; MPI; SKJ); Colic (f; DEM; KAP); Coma (f; MPI; WOI); Condyloma (f; JLH); Constipation (f; DEP; HHB; KAB); Convulsion (f; PR13:561); Cough (1; KAB; MPI; WOI); Cystosis (f; JLH); Diabetes (1; MPI); Diarrhea (f; MPI; SKJ); Dropsy (f; HHB); Drowsiness (f; MPI; WOI); Dysentery (f; WOI); Dysmenorrhea (f; DEP); Dyspepsia (f; MPI); Edema (1; MPI); Enterosis (f; DEP; JLH); Epilepsy (f; MPI; WOI); Fever (f; DEM; SKJ; SUW); Fungus (1; KAP); Gas (f; DEP; KAB; SUW; WOI); Gastrosis (f; JLH); Giardia (1; PR13:561); Gingivosis (f; JLH); Gout (f; DEP; MPI); Hemorrhoid (f; MPI); Hepatosis (f; DEP; JLH); Hoarseness (f; DEP); Immunodepression (1; PR13:561); Induration (f; JLH); Infection (1; KAP); Inflammation (1; MPI; WOI); Insomnia (f; MPI; WOI); Ischiosis (f; HHB); Leprosy (f; WOI); Leukoderma (f; MPI); Lumbago (f; DEP; KAB; MPI); Mastosis (f; JLH); Myalgia (f; WOI); Mycosis (f; KAP); Nervousness (f; MPI; WOI); Nyctalopia (f; DEP); Ophthalmia (f; KAB); Pain (1; SKJ; WOI); Palsy (f; DEP; KAP; MPI); Paralysis (f; HHB; KAB; SKJ); Paraplegia (f; DEP; KAB); Puerperium (f; SKJ); Pulmonosis (f; DEP); Rheumatism (f; HHB; MPI); Salmonella (1; MPI); Sciatica (f; DEP; KAB); Sclerosis (f; JLH); Snakebite (f; DEP); Sore Throat (f; JLH); Splenosis (f; KAB; MPI; SKJ); Staphylococcus (1; MPI); Stomatosis (f; JLH); Swelling (f; DEP); Tetanus (f; DEP); Thirst (f; SKJ); Tuberculosis (1; KAP; MPI); Uvulosis (f; JLH); Wart (f; JLH); Worm (1; HHB; KAB; KAP; MPI).

Dosages (Long Pepper) :
No modern dosages uncovered. 1–2 g ground fruit could provide biologically active levels of piperine. Old peppers are believed to be more medicinally active than fresh peppers (DEP).

Extracts (Long Pepper) :
Alcoholic extracts of fruits and aqueous leaf extract active against Escherichia coli and Micrococcus pyogenes. In human volunteers, 20 mg piperine increases bioavailability of curcumin 20-fold (MAB). Long pepper may contain 2% piperine suggesting that 1 gram of long pepper could increase availability of curcumin 20-fold. Milk extract effectively reduced passive cutaneous anaphylaxis in rats. Ether extracts and fruits are decoction antiedemic and antiinflammatory. Root powder at 100 mg/kg completely reduced fertility in rats on days 6 to 9 of pregnancy. 50% ethanolic extract is antispasmodic and hypoglycemic. N-isobutyl-decatrans2, trans4-dienamide active against Mycobacterium tuberculosis in vitro and in vivo ( = 20% as potent as streptomycin). EO active against Bacillus cereus, B. subtilis, Escherichia coli, Mycobacterium tuberculosis, Salmonella thypi, Sar. lutea Shigella boydi, S. dysenteriae, Staphylococcus albus, S. aureus, and Vibrio cholera. EO fungicidal against Aspergillus flavus, Curvularia lunata, Penicillium javanicum, P. striatum, and Trichoderma viridi. Oil anthelmintic to Ascaris lumbricoides. Crude extracts (and piplartine) suppressed ciliary movements in frog esophagus suggesting that it might suppress the cough reflex in humans (MPI). Piperine may be used as an analeptic in morphine poisoning, in lieu of nalorphine, especially if analgesia is desired (MPI).