LESSER PERIWINKLE VINCA MINOR

LESSER PERIWINKLE (Vinca minor L.) +

Activities (Lesser Periwinkle) :
Anesthetic (1; HH2; WBB); Antialzheimeran (1; FNF); Antibacterial (f; CRC); Anticholinesterase (1; HH2); Antidementic (1; FNF); Antilactagogue (f; BRU; CRC); Antiscorbutic (f; WBB); Antispasmodic (1; CRC; PH2; WOI); Astringent (f; APA; BRU; CRC; WBB); Bitter (f; KOM; PH2); Bradycardic (1; WBB); Carminative (f; CRC; WBB); Cerebroprotective (f; APA); CNS Depressant (1; WBB); Collyrium (f; CRC); Cytotoxic (1; HH2); Depurative (f; CRC; KOM; WBB; WOI); Diuretic (f; CRC; KOM; WOI); Emetic (f; WOI); Emmenagogue (f; CRC); Hemostat (f; APA; KOM; WOI); Hypoglycemic (1; HH2; PH2); Hypotensive (1; APA; CRC; PH2); Immunodepressant (1; APA); Immunostimulant (1; APA; HH2); Lactagogue (f; CRC); Laxative (f; CRC; GMH); Leukocytopenogenic (1; KOM); Memorigenic (1; APA; BRU; FNF; PH2); Negative Chronotropic (1; PH2); Parasympatholytic (1; HH2); Peristaltic (1; WBB); Phagocytotic (1; HH2); Philtre (f; CRC); Sedative (1; CRC; KOM); Sympatholytic (1; PH2); Tonic (f; CRC; WOI); Vermifuge (f; CRC; WOI); Vulnerary (f; BRU; KOM).

Indications (Lesser Periwinkle) :
Abscess (f; PH2); ADHD (1; BRU); Alzheimer’s (1; BRU; FNF); Angina (f; KOM); Bacteria (f; CRC); Bleeding (f; APA; CRC; HH2; KOM; PH2; WOI); Brain (f; PHR); Bruise (f; PH2); Cancer (1; CRC); Cancer, uvula (f; CRC; JLH); Catarrh (f; CRC; HH2; KOM; MAD); Chlorosis (f; MAD); Circulosis (f; PH2); Congestion (f; GMH); Constipation (f; CRC; GMH); Cramp (1; CRC; GMH; PH2; WOI); Cystosis (f; PH2); Debility (f; KOM); Dementia (1; BRU; FNF); Dermatosis (f; BRU; CRC; MAD); Diabetes (1; PH2); Diarrhea (f; CRC; HH2; KOM; MAD; PH2; WBB); Dizziness (f; APA); Dropsy (f; KOM); Dysentery (f; CRC; WBB); Dysmenorrhea (f; APA; MAD); Eczema (f; CRC; HH2; PH2); Encephalosis (f; PHR); Enterosis (f; APA; HH2; MAD; PH2); Epistaxis (f; CRC; GMH; HH2; PH2); Fever (f; MAD); Fit (f; CRC); Gas (f; MAD); Gastrosis (f; HH2; PH2); Headache (f; APA; CRC); Hemorrhoid (f; CRC; GMH); Hepatosis (f; MAD); High Blood Pressure (2; APA; CRC; PH2; WOI); Hyperglycemia (1; HH2; PH2); Hysteria (f; CRC; GMH); Immunodepression (1; APA; HH2); Inflammation (f; APA; GMH; KOM); Insomnia (1; CRC; KOM); Menorrhagia (f; CRC); Migraine (f; CRC); Mucososis (f; PH2); Nephrosis (f; MAD); Nervousness (1; CRC; KOM); Neurosis (f; APA; CRC); Nightmare (f; . GMH); Ophthalmia (f; WOI); Pain (1; HH2; WBB); Pharyngosis (f; KOM); Phthisis (f; WBB; WOI); Seborrhea (f; WOI); Senility (1; APA; PH2); Sore (f; MAD); Sore Throat (f; APA; MAD; PH2); Stroke (1; APA); Tinnitus (1; BRU); Tonsilosis (f; KOM); Toothache (f; KOM; MAD); Trichomoniasis (f; CRC); Tuberculosis (f; MAD); Uvulosis (f; JLH); Vaginosis (f; CRC; KOM); Vertigo (1; BRU); Water Retention (1; MAD); Weakness (f; KOM); Worm (f; CRC; WOI); Wound (f; APA).

Dosages (Lesser Periwinkle) :
2–4 g powdered herb (PNC); 200 ml boiling water over 1 tsp herb, 2–3 cups/day (PH2); 15 g herb/250 ml water for infusion (PH2); macerate 100 g herbs in a liter of wine, steep 10 days (PH2); 2.5–5 ml liquid herb extract (PNC); 2–5 g fluid extract (MAD).

Contraindications, Interactions, and Side Effects (Lesser Periwinkle):
Class 2d. Contraindicated in constipation and hypotension (AHP). “Health hazards not known with proper therapeutic dosages” (PH2). Commission E reports hematological changes (e.g., leucocytopenia, lymphocytopenia, reduced globulin levels) have been observed in animals (AEH). Little cited as allergic or toxic (CRC). PH2 reports skin flushing and GI disturbances. Overdose may seriously lower blood pressure (PH2). LD50 “drug” 1400 mg/kg ipr mouse (HH2), LD50 “mixed alkaloids” 76 mg/kg ipr mouse (HH2), LD50 “mixed alkaloids” 24 mg/kg ivn mouse (HH2), LD50 “mixed alkaloids” 500 mg/kg orl mouse (HH2).