JATAMANSI INDIAN NARD NARDOSTACHYS

JATAMANSI, INDIAN NARD (Nardostachys grandiflora DC.) ++

Synonym:
- Nardostachys jatamansi auct.

Activities (Jatamansi) :
- Alexeteric (f; KAB); Antiarrhythmic (1; MPI); Antibacterial (1; MPI); Anticonvulsant (1; PH2; MPI); Antidote (f; PH2); Antiemetic (1; KAP); Antiestrogenic (1; MPI); Antihistaminic (1; MPI); Antipyretic (f; KAB); Antiseptic (1; MPI; SKJ; SUW); Antiserotonin (1; MPI); Antispasmodic (1; DEP; KAB; MPI); Antiulcer (1; HH2; PH2); Aperitif (f; KAB); Bitter (f; KAB; SUW); Bronchodilator (1; MPI); Candidicide (1; MPI); Carminative (f; KAB; SUW); CNS-Depressant (f; MPI); Deobstruent (f; DEP; MPI); Depurative (f; DEP; KAB); Diuretic (f; DEP; KAB; MPI; SUW); Emmenagogue (1; AHP; KAB; SUW); Fungicide (1; KAP;
MPI); Hypotensive (1; KAP; MPI); Laxative (f; KAB; SKJ; SUW); Lipogenic (f; KAB); Pectoral (f; KAB); Propecic (f; DEP; KAB; MPI); Sedative (2; MPI; SKJ); Stimulant (f; KAB; MPI; SUW); Stomachic (f; KAB; SUW); Taenicide (1; MPI); Tonic (f; DEP; KAB; SUW); Tranquilizer (1; KAP; MPI); Uterotonic (1; AHP); Vermifuge (1; MPI).

Indications (Jatamansi) :
- Attention-Deficit Disorder (2; MPI); Aggressiveness (1; KAP); Alopecia (f; KAB; MPI); Anorexia (f; KAB); Arrhythmia (1; MPI); Asthma (1; MPI); Bacteria (1; MPI); Biliousness (f; KAB); Bite (f; KAB); Bronchosis (1; KAB; MPI; SKJ); Candida (1; MPI); Cardiopathy (1; KAB; MPI); Chorea (f; MPI); Cholera (1; DEP; MPI; SUW); Circulosis (f; MPI); Colic (f; KAB; MPI; SUW); Complexion (f; KAB); Constipation (f; KAB; SKJ; SUW); Convulsion (1; DEP; KAB; MPI; PH2; SKJ; SUW); Cough (f; KAB; MPI); Cramp (1; DEP;
KAB; MPI; PH2); Dermatosis (f; KAB); Dysmenorrhea (f; SKJ); Dyspnea (1; MPI); Dysuria (f; SKJ); Enterosis (f; KAB; PH2; SUW); Epilepsy (f; DEP; KAB; PH2; SUW); Erysipelas (f; KAB); Escherichia (1; MPI); Fever (f; KAB); Fungus (1; KAP; MPI); Gas (f; DEP; KAB; KAP; PH2; SUW); Gastrosis (f; KAP; PH2); Gleet (f; KAB); Gray Hair (f; DEP); Headache (f; KAP; PH2); Hepatosis (f; PH2); High Blood Pressure (2; KAP; MPI); Hyperkinesis (2; MPI); Hysteria (f; DEP; KAB; SUW); Infection (1; KAP; MPI); Inflammation (f; KAB; PH2); Insomnia (2; HH2; MPI; PH2; SKJ); Jaundice (f; DEP; PH2); Leprosy (f; KAB; MPI); Lumbago (f; KAB); Madness (f; MPI); Menopause (f; PH2); Mycosis (1; KAP; MPI); Nausea (f; PH2); Nephrosis (f; KAB; PH2); Nervousness (2; KAP; MPI; SKJ); Neurasthenia (1; MPI); Neurosis (f; PH2); Ophthalmia (f; PH2); Pain (f; KAB; PH2); Palpitation (1; DEP; KAB; MPI; WOI); Respirosis (f; DEP); Rhinosis (f; SKJ); Salmonella (1; MPI); Smallpox (f; MPI; SKJ); Snakebite (f; KAB); Sore (f; KAB; MPI); Sore Throat (f; KAB); Staphylococcus (1; MPI); Sting (f; KAP); Stomachache (f; PH2); Tachycardia (1; MPI; WOI); Tapeworm (1; MPI); Tuberculosis (f; SKJ); Ulcer (1; HH2; PH2); Uterosis (f; PH2); Vomiting (1; KAP); Water Retention (f; DEP; KAB; MPI; SUW); Worm (1; MPI); Yeast (1; MPI).

Dosages (Jatamansi) :
- 1 - 1.5 g powdered herb (KAP); 0.6 - 1.3 drug as single dose (PH2); 5 g root 3 ×/day (PH2); 10 - 20 grains powdered root (DEP; HH2); 14 - 56 ml fluid extract (KAP); 28 - 56 ml infusion (KAP); 28 - 56 ml decoction (KAP); wineglass full 3 ×/day (1:10 tincture or 1:40 infusion with 2 g maximum per single dose) (PH2).

Contraindications, Interactions, and Side Effects (Jatamansi) :
- Class 2b. Emmenagogue and uterine stimulant (AHP). Contraindicated during pregnancy (PH2). Health hazards not known with proper therapeutic dosages (PH2).

Extracts (Jatamansi) :
- LD50 of jatamansone (ipr mouse) 350 mg/kg, cf 900 mg/kg for the whole EO (MPI). EO hypotensive in dogs, dosages for hypotensive humans, less than lab animal dosage (MPI). Preliminary clinical trials of jatamansone exhibited reduced aggressiveness, restlessness, stubbornness, as well as less insomnia (MPI). With 28 hyperkinetic children, jatamansone and placebo were compared for 11 months, with D-amphetamine and chlorpromazine. Jatamansone and especially amphetamine significantly improved behavior, amphetamine was better helping aggressiveness and restlessness. Children with mental retardation showed little response to any of the drugs. Jatamansone had fewer side effects than the pharmaceuticals. Amphetamine exacerbated symptoms early on and caused insomnia in one patient (MPI).