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Herbal Medicine
JABORANDI (Pilocarpus spp) + PHR covered Pilocarpus microphyllus Stapf ex Wardleworth.
Activities (Jaborandi) : - Allergenic (f; CRC); Anesthetic (f; PH2); Antidote, atropine (1; CRC); Cardiodepressant (1; CRC); Cholimimetic (1; CRC); Diaphoretic (1; CRC; PHR; PH2); Emetic (f; CRC; PH2); Gastrostimulant (1; PHR; PH2); Lacrimatory (1; CRC; PH2); Lactagogue (f; CRC); Mitotic (1; CRC); Myostimulant (1; PH2); Parasympathomimetic (1; CRC; PH2); Peristaltic (1; CRC) ; Poison (f; CRC); Secretagogue (1; PH2); Sialagogue (1; CRC; PHR; PH2); Teratogenic (f; CRC).
Indications (Jaborandi) : - Alopecia (f; CRC); Asthma (f; CRC); Brights Disease (f; CRC); Catarrh (f; CRC); Convulsion (f; PH2); Deafness (f; CRC); Diabetes (f; CRC); Diarrhea (f; PHR); Dropsy (f; CRC); Enterosis (f; CRC; PH2); Epilepsy (f; PH2); Fever (1; CRC; PHR; PH2); Flu (f; PH2); Gastrosis (f; PH2); Glaucoma (1; PHR; PH2); Gonorrhea (f; PH2); Heart (f; CRC); Hepatosis (f; CRC); Inflammation (f; PH2); Itch (f; CRC); Ischuria (f; PH2); Jaundice (f; CRC); Nausea (f; CRC); Nephrosis (f; CRC; PH2); Neurosis (f; PH2); Pain (f; PH2); Pleurisy (f; CRC); Pneumonia (f; PH2); Psoriasis (f; CRC; PH2); Rheumatism (f; CRC); Syphilis (f; CRC); Thirst (f; CRC); Tonsilosis (f; CRC); VD (f; CRC).
Contraindications, Interactions, and Side Effects (Jaborandi) : - Class 2b (AHP). Hazards and/or side effects not known for proper therapeutic dosages (PH2) (but PH2 designates no specific quantified dosage! JAD). Not for use during pregnancy (PH2). The lethal dose of pilocarpine is ca 60 mg, corresponding to 5 - 10 g drug (PHR). My database suggests that it is much less toxic; LD50 pilocarpine = 911 mg/kg orl rat. Poisoning possible through eye drops being swallowed through eye or nose. May cause bradycardia, bronchial cramps, colic, convulsion, diaphoresis, dyspnea, emesis, hypotension, and salivation (PH2).
Hit: 404
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