Dosages (Hierba Santa) : - Infusion of 1/2 leaf taken after a meal as a stomachic (JFM); one leaf in sweetened water (180 cc) (JFM); 15 - 30 drops tincture (10 g leaf in 150 cc alcohol) every 3 hours (JFM).
Contraindications, Interactions, and Side Effects (Hierba Santa) : - Not covered (AHP; EFS; IED; KOM; PH2). Very rich in the carcinogen safrole.
Extracts (Hierba Santa) : - At 0.1 ml/kg intravenously in dogs, the aqueous extract is hypotensive (TRA). The 95% ethanolic extract at 0.33 ml/l is spasmogenic and uterotonic in vitro (TRA). At 3 ml/l, the aqueous extracts have a vasodilator effect on lab rats (TRA). Safrole and elemicin may exert hallucinogic and/or psychotropic activities (TRA). Myrcene has antinociceptive activities. As an alpha-2-adrenergic agonist, myrcene affects arterial blood pressure (TRA).
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