Dosages (Gymnema) : - 1 - 2 tbsp fresh leaf (PED); 2 - 3 g dry leaf (PED); 2 g dry leaf:10 ml alcohol/10 ml water (PED); 2 - 4 g powdered leaf (KAP); 2 - 4 g powdered leaf/day (SKY); 14 - 28 ml leaf decoction (KAP); 5 - 10 ml/day 1:1 extract (KEB); 1 - 2 ml/day to decrease cravings for sweets (KEB); 400 mg water-soluble acidic fraction in India (SKY).
Contraindications, Interactions, and Side Effects (Gymnema) : - Not covered (AHP; KOM). Generally safe and devoid of side effects at indicated levels; safety in lactation and pregnancy undetermined; should be used for diabetes under the purview of a practitioner; not to be used in place of insulin (SKY). Gymnema leaves raise insulin levels in healthy volunteers; leaves also lower serum cholesterol and triglycerides (SKY); water soluble acidic fractions are hypoglycemic (SKY). Gymnema given orally proved as potent as tolbutamide in lowering blood sugar, and keeping it low, in a 1-month study (APA).
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