Contraindications, Interactions, and Side Effects (Guaiacum) : - Not covered (AHP). Hazards and/or side effects not recorded for proper therapeutic dosages (PH2). None known (KOM). CAN caution that the lignans are allergenic and may cause dermatosis. Recommended that people with allergy, hypersensitive or acute inflammatory conditions avoid it. Avoid use when pregnant or lactating (CAN). High doses may cause colic, diarrhea, and other GI complaints (PHR). Resin LD50 = >5000 mg/kg orl rat.
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