GROUNDSEL SENECIO VULGARIS

GROUNDSEL (Senecio vulgaris L.) X

Madaus, rightly or wrongly, says that S. jacobaea and S. vulgaris have the same effects. So
most of the MAD entries below have also been transcribed to S. vulgaris and may really belong
only there.

Activities (Groundsel) :
- Carcinogenic (1; AEH; PH2); Diaphoretic (f; EFS); Diuretic (f; EFS); Emetic (f; EFS); Emmenagogue (f; EFS); Hemostat (f; EFS; MAD); Hepatotoxic (1; AEH; PH2); Laxative (f; EFS); Poison (1; PH2); Vermifuge (f; EFS); Vulnerary (f; EFS).

Indications (Groundsel) :
- Amenorrhea (f; EFS; MAD); Anemia (f; MAD); Bleeding (f; EFS; MAD); Catarrh (f; MAD); Chlorosis (f; MAD); Colic (f; HH2); Constipation (f; EFS); CVI (f; BRU); Cystosis (f; MAD); Depression (f; MAD); Diabetes (f; MAD); Diarrhea (f; MAD); Dysmenorrhea (f; EFS; HH2; MAD; PH2); Encephalosis (f; MAD); Epilepsy (f; HH2); Fever (f; EFS); Gout (f; MAD); Headache (f; MAD); Hemorrhoid (f; MAD); Jaundice (f; MAD); Mastosis (f; MAD); Neurosis (f; MAD); Odontosis (f; HH2); Pain (f; MAD); Phthisis (f; MAD); Plethora (f; MAD); Scab (f; MAD); Sore (f; MAD); Spine (f; MAD); Tuberculosis (f; MAD); Urogenitosis (f; MAD); Uterosis (f; MAD); Water Retention (f; EFS); Worm (f; EFS; HH2); Wound (f; EFS).

Dosages (Groundsel) :
- Do not take it (JAD); 2 g tincture several ×/day, up to 15 g (MAD); 1 - 3 fl extract (MAD); 40 - 60 g juice (MAD).

Contraindications, Interactions, and Side Effects (Groundsel) :
- Not covered (AHP). Contains pyrrolizidine alkaloids (PAs) in considerable amounts and varieties, which can be carcinogenic, hepatotoxic, and mutagenic. Use of Senecio species can result in potentially fatal hepatic veno-occlusive disease in humans, with symptoms of abdominal pain and vomiting with ascites.
PAs are toxic to humans, with liver damage with cirrhosis and ascites, or seneciosis, or venoocclusive
disease reported in almost all cases of severe or fatal intoxications, from intakes of 0.5 mg/kg to 3.3 mg/kg (AEH1). Horses grazing the plant develop anorexia, ascites, edema, encephalopathy with gait anomalies, and jaundice (BRU). LD50 (mixed alkaloids) = 140 mg/kg orl rat (HH2).