GOLDTHREAD COPTIS SPP

GOLDTHREAD (Coptis spp.) +

Coptis chinensis Franch., Coptis deltoides C.Y. Cheng & Hsiao, Coptis japonica (Thunb.) Makino, or other berberine-containing species of the same genus (WHO), which would include Indias Coptis teeta Wall., and our American Coptis trifolia (L.) Salisb.

Activities (Goldthread) :
Alexeteric (f; DAA); Amebicide (1; WHO); Analgesic (1; DAA); Antiacetylcholinesterase (1; WHO); Antialzheimeran (1; COX; FNF); Antiarthritic (1; COX; FNF); Antibacterial (1; WHO); Anticancer (1; COX; FNF); Antidote, daylily (f; FAY); Antidysenteric (1; DAA; WHO); Antigiardic (1; X2131648); Antihelicobacter (1; X9781854); Antiinflammatory (1; COX; DAA); Antiperiodic (1; PNC); Antiperistaltic (1; FNF); Antipyretic (f; DAA); Antisecretory (1; WHO); Antiseptic (1; DAA; WHO); Antitrypanosomic (1; X9121161); Antiulcer (1; X9781854); Astringent (1; DEM); Bitter (1; DAA); cAMP-Inhibitor (1; WHO); Candidicide (1; X2079677); Collyrium (f; DAA; DEM); Digestive (1; PH2; PNC); Hypoglycemic (1; WHO); Mutagenic (1; PH2); Stomachic (f; DAA; SKJ); Tonic (1; FEL; MIC; PH2; PNC); Trichomonicide (1; WHO; X2131648).

Indications (Goldthread) :
Adenopathy (f; JLH); Alcoholism (f; FAD; FEL); Alzheimers (1; COX; FNF); Ameba (1; WHO); Amebiasis (1; WHO); Anorexia (f; MIC); Anxiety (f; DAA); Aphtha (f; DAA); Arthrosis (1; COX; DAA; FNF; WHO); Backache (f; SKJ); Bacteria (1; WHO); Biliousness (f; DEM); Boil (1; DAA; WHO); Burn (f; WHO); Cancer (1; COX; DAA; FNF; JLH); Cancer, gland (1; COX; JLH); Cancer, nose (1; COX; JLH); Cancer, pharynx (1; COX; JLH); Cancer, stomach (1; COX; JLH; MIC); Cancer, thyroid (1; COX; JLH); Candida (1; FAD;
X2079677); Canker (1; DAA; DEM); Chafing (f; MIC); Cholera (1; WHO); Cold (f; DEM; FAY); Conjunctivosis (1; DAA; FAD; WHO); Cough (f; DEM); Cramp (f; DAA; DEM; FAD); Debility (f; SKJ); Dentition (f; DEM); Dermatosis (1; DAA; WHO); Diabetes (1; DAA; WHO); Diarrhea (1; DEM; MIC; WHO); Diphtheria (1; DAA); Dysentery (1; DAA; WHO); Dysmenorrhea (1; WHO); Dyspepsia (f; DEM; FAD; FEL); Earache (f; DEM); Eczema (1; DAA); Edema (1; DAA); Enterosis (1; DAA; WHO); Epistaxis (f; DAA); Escherichia (f; HHB); Fever (f; DAA); Gastrosis (1; DEM; FAD; FEL; WHO); Gingivosis (f; DEM); Gout (1; WHO); Helicobacter (1; X9781854); Hematemesis (f; DAA); Hemoptysis (f; DAA); Hemorrhoid (f; DAA); Hepatosis (f; DAA); Infection (1; DAA; DEM); Inflammation (1; COX; DAA; FAD; FEL; FNF); Insomnia (f; DAA); Jaundice (f; DEM; FAD); Leishmaniasis (1; WHO); Leukemia (f; JLH); Malaria (f;
SKJ; WOI); Nausea (f; DAA; DEM; FAD); Nephrosis (f; WHO); Ophthalmia (1; DEM); Otitis Media (1; DAA); Pain (1; DAA; DEM); Pertussis (1; DAA); Respirosis (1; DEM); Salmonella (1; HHB); Scabies (f; DAA); Scarlet Fever (1; DAA); Sore (f; DAA; DEM); Sore Throat (1; DEM; FAD); Stomachache (f; DAA); Stomatosis (f; DEM; FEL); Streptococcus (1; HHB); Syphilis (f; DAA); Toothache (1; DAA; WHO); Trench Mouth (f; DEM); Trichomoniasis (1; WHO); Tuberculosis (1; DAA); Ulcer (1; X9781854); Vaginosis (1; DAA); VD (f; DEM); Vertigo (f; DEM); Worm (f; DEM); Yeast (1; FAD; X2079677).

Dosages (Goldthread) :
0.5 - 1.2 g powdered rhizome; 2 - 4 ml liquid extract (PNC); 1.5 - 6 g crude drug/day (WHO).

Contraindications, Interactions, and Side Effects (Goldthread) :
Class 2b. Emmenagogue/uterine stimulant (AHP). Not covered (KOM). Hazards and/or side effects not known for proper therapeutic dosages (PH2). Berberine is reportedly mutagenic in yeast cells and Ames test (intercalation into the DNA). Not for use during pregnancy (PH2). If Barney is right in saying that
goldenseal should not be taken for long periods of time, I suspect that the same would be true for those herbs containing similar compounds like barberry, goldthread, oregon grape, and yellowroot.
Therefore, I lowered their safety ratings to 1 + (Barney, 1996). Coptis said to be as effective as, or more so than, sulfonamides at curing the following: acute extraocular inflammation, bacillary dysentery, diphtheria, eczema, enterosis, pertussis, pulmonary tuberculosis, purulent otitis media, surgical pyrogenic infections, and trichomoniasis vaginalis (DAA). Also said to be the best source of the COX-2 inhibitor, berberine (COX; FNF).