Contraindications, Interactions, and Side Effects (Fo-Ti) : - Class 2d. Raw root is laxative; prepared root may cause GI distress; contraindicated with diarrhea (AHP). May cause colic, diarrhea, nausea, numbness of the extremities, and skin rashes (AHP; SKY). Allergic cystosis may result (LAF). Emodin has vasodilator and immunosuppressive effects in test tubes. LD50 of alcoholic percolates 169 to 2700 mg/kg (raw to cured) (LAF).
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