Contraindications, Interactions, and Side Effects (China Rose) : - Internal uses contraindicated in small children and pregnant or lactating women (TRA). Hydroethanolic extract LD50 1000 ppm (TRA).
Contraindications, Interactions, and Side Effects (Chinese Club Moss) : - Pregnant women, and people with hypertension or pulmonary problems due to increased bronchial secretions should not take it. Said to have a high therapeutic index with few side effects (ABS).
Extracts (Chinese Club Moss) : - Huperzine A reversibly binds acetylcholinesterase (AChE), preventing it from breaking down acetylcholine, and thus preventing a deficiency and improving mental function (ABS). It binds with a half-life of 4.8 hours. Its effect may persist 8 hours, longer than donepezil and tacrine, FDA-approved drugs for Alzheimers. Huperzine As distinct mode of action is said to maintain and improve memory.
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